Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1

Neeltje van Doremalen; Trenton Bushmaker; Dylan Morris; Myndi Holbrook; Amandine Gamble; Brandi Williamson; Azaibi Tamin; Jennifer Harcourt; Natalie Thornburg; Susan Gerber; Jamie Lloyd-Smith; Emmie de Wit; Vincent Munster

HCoV-19 was most stable on plastic and stainless steel and viable virus could be detected up to 33 72 hours post application ( Figure 1A ), though the virus titer was greatly reduced (plastic from 10 3.7 to 34 10 0.6 TCID 50 /mL after 72 hours, stainless steel from 10 3.7 to 10 0.6 TCID 50 /mL after 48 hours). SARS-CoV-35 1 had similar stability kinetics (polypropylene from 10 3.4 to 10 0.7 TCID 50 /mL after 72 hours, stainless steel 36 from 10 3.6 to 10 0.6 TCID 50 /mL after 48 hours). No viable virus could be measured after 4 hours on copper 37 for HCoV-19 and 8 hours for SARS-CoV-1, or after 24 hours on cardboard for HCoV-19 and 8 hours for 38 SARS-CoV-1 ( Figure 1A ). This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available author/funder, who has granted medRxiv a license to display the preprint in perpetuity.