Author: Richard K. Babbs; Jacob A. Beierle; Julia C. Kelliher; Rose Medeiros; Jeya Anandakumar; Anyaa Shah; Emily J. Yao; Melanie M. Chen; Camron D. Bryant
Title: The demyelinating agent cuprizone induces a male-specific reduction in binge eating in the binge-prone C57BL/6NJ strain Document date: 2019_12_5
ID: 3l8pm0t5_22
Snippet: We observed a decrease in MBP in the BE-prone B6NJ substrain versus BE-resistant B6J 368 substrain that was significant for the14 kDa isoform (Fig.5) and was consistent with our previous 369 observation of an association of BE with the downregulated expression of a set of genes enriched 370 for myelination (Kirkpatrick et al., 2017) . In that study, the enrichment was identified as a function An additional factor that could contribute to sex diff.....
Document: We observed a decrease in MBP in the BE-prone B6NJ substrain versus BE-resistant B6J 368 substrain that was significant for the14 kDa isoform (Fig.5) and was consistent with our previous 369 observation of an association of BE with the downregulated expression of a set of genes enriched 370 for myelination (Kirkpatrick et al., 2017) . In that study, the enrichment was identified as a function An additional factor that could contribute to sex differences in the effect of cuprizone on 392 BE is weight loss-induced rebound hyperphagia. We are unaware of any studies demonstrating 393 sex differences in eating behavior after weight loss in rodentswith or without cuprizone. 394
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