Author: Kipshidze, Nicholas; Yeo, Nick; Kipshidze, Nodar
Title: Photodynamic and Sonodynamic Therapy of Acute Hypoxemic Respiratory Failure in Patients with COVID-19 Cord-id: b4zo4nmk Document date: 2020_8_17
ID: b4zo4nmk
Snippet: • COVID-19 is largely localized in lungs. • SARS-CoV-2 binds to the heme groups in hemoglobin that leads to severe hypoxia. • Considering the unique challenges of COVID-19 we propose the use of PDT. • Porphyrin-based photosensitizers (PS) act as a ‘decoy’ in which the SARS-CoV-2 virions would attach to PS molecules. • Photoactivation capable of destroying the bonded SARS-CoV-2 virions; • PDT combined with an existing therapy may prove the most effective approach. • Pre-clinical
Document: • COVID-19 is largely localized in lungs. • SARS-CoV-2 binds to the heme groups in hemoglobin that leads to severe hypoxia. • Considering the unique challenges of COVID-19 we propose the use of PDT. • Porphyrin-based photosensitizers (PS) act as a ‘decoy’ in which the SARS-CoV-2 virions would attach to PS molecules. • Photoactivation capable of destroying the bonded SARS-CoV-2 virions; • PDT combined with an existing therapy may prove the most effective approach. • Pre-clinical and clinical studies need to be performed to determine the feasibility, safety, and efficacy of this approach.
Search related documents:
Co phrase search for related documents- locally systemically and lung inflammation: 1
- lung cancer and macular degeneration: 1
Co phrase search for related documents, hyperlinks ordered by date