Prevalence of SARS-CoV-2 among high-risk populations in Lomé (Togo) in 2020

Halatoko, Wemboo Afiwa; Konu, Yao Rodion; Gbeasor-Komlanvi, Fifonsi Adjidossi; Sadio, Arnold Junior; Tchankoni, Martin Kouame; Komlanvi, Koffi Segbeaya; Salou, Mounerou; Dorkenoo, Ameyo Monique; Maman, Issaka; Agbobli, Amétépé; Wateba, Majesté Ihou; Adjoh, Komi Séraphin; Goeh-Akue, Edem; Kao, Yem-bla; Kpeto, Innocent; Pana, Paul; Kinde-Sossou, Rebecca; Tamekloe, Agbeko; Nayo-Apétsianyi, Josée; Assane, Simon-Pierre Hamadi; Prine-David, Mireille; Awoussi, Sossinou Marcel; Djibril, Mohaman; Mijiyawa, Moustafa; Dagnra, Anoumou Claver; Ekouevi, Didier Koumavi

BACKGROUND: In December 2019, the COVID-19 outbreak began in China and quickly spread throughout the world and was reclassified as a pandemic in March 2020. The first case of COVID-19 was declared in Togo on March 5. Two months later, few data were available to describe the circulation of the new coronavirus in the country. OBJECTIVE: This survey aimed to estimate the prevalence of SARS-CoV-2 in high-risk populations in Lomé. MATERIALS AND METHODS: From April 23, 2020, to May 8, 2020, we recruited a sample of participants from five sectors: health care, air transport, police, road transport and informal. We collected oropharyngeal swabs for direct detection through real-time reverse transcription polymerase chain reaction (rRT-PCR) and blood for antibody detection by serological tests. The overall prevalence (current and past) of infection was defined by positivity for both tests. RESULTS: A total of 955 participants with a median age of 36 (IQR 32–43) were included, and 71.6% (n = 684) were men. Approximately 22.1% (n = 212) were from the air transport sector, 20.5% (n = 196) were from the police sector, and 38.7% (n = 370) were from the health sector. Seven participants (0.7%, 95% CI: 0.3–1.6%) had a positive rRT-PCR test result at the time of recruitment, and nine (0.9%, 95% CI: 0.4–1.8%) were seropositive for IgM or IgG against SARS-CoV-2. We found an overall prevalence of 1.6% (n = 15), 95% CI: 0.9–2.6%. CONCLUSION: The prevalence of SARS-CoV-2 infection among high-risk populations in Lomé was relatively low and could be explained by the various measures taken by the Togolese government. Therefore, we recommend targeted screening.