Author: Lulin Zhou; Zubiao Niu; Xiaoyi Jiang; Zhengrong Zhang; You Zheng; Zhongyi Wang; Yichao Zhu; Lihua Gao; Xiaoning Wang; Qiang Sun
Title: Systemic analysis of tissue cells potentially vulnerable to SARS-CoV-2 infection by the protein-proofed single-cell RNA profiling of ACE2, TMPRSS2 and Furin proteases Document date: 2020_4_10
ID: 3btc31kj_35
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.06.028522 doi: bioRxiv preprint Furin genes ( Figure 4H ). By contrast, in thyroid, there was little expression of the ACE2 genes in despite of the highly expression of TMPRSS2 and Furin ( Figure S3I -J), which disagrees with the IHC results that ACE2 is highly expressed in stromal cells of thyroid gland ( Figure S2G ). These results show.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.06.028522 doi: bioRxiv preprint Furin genes ( Figure 4H ). By contrast, in thyroid, there was little expression of the ACE2 genes in despite of the highly expression of TMPRSS2 and Furin ( Figure S3I -J), which disagrees with the IHC results that ACE2 is highly expressed in stromal cells of thyroid gland ( Figure S2G ). These results show that the heart and fetal adrenal gland are more likely vulnerable to the SARS-CoV-2 virus via cardiomyocytes and HLC cells, respectively.
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