Selected article for: "cell stress granule and mm sodium"

Author: Michael M. Lutz; Megan P. Worth; Meleana M. Hinchman; John S. L. Parker; Emily D. Ledgerwood
Title: Mammalian orthoreovirus infection is enhanced in cells pre-treated with sodium arsenite
  • Document date: 2019_2_20
  • ID: cpfwzudq_14
    Snippet: have suggested that reovirus-induced stress granule formation is cell-type specific [15, 292 16] . Therefore, we next sought to determine if the replication enhancement observed in 293 CV-1 cells was seen in other cell types. We assessed the effect of pre-treatment with 0.5 294 mM sodium arsenite on CV-1, HeLa, L929 murine fibroblasts, and human pancreatic 295 ductal epithelial (HPDE) cells on viral infectivity. In each cell line, a relative mult.....
    Document: have suggested that reovirus-induced stress granule formation is cell-type specific [15, 292 16] . Therefore, we next sought to determine if the replication enhancement observed in 293 CV-1 cells was seen in other cell types. We assessed the effect of pre-treatment with 0.5 294 mM sodium arsenite on CV-1, HeLa, L929 murine fibroblasts, and human pancreatic 295 ductal epithelial (HPDE) cells on viral infectivity. In each cell line, a relative multiplicity 296 of infection was chosen such that 20-50% of cells were infected. Consistent with our 297 observations in CV-1 cells, pre-treatment with sodium arsenite in L929 and HPDE cells 298 resulted in a higher percentage of cells exhibiting viral factories than untreated cells 299 All rights reserved. No reuse allowed without permission.

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