Author: Lucia Grenga; Fabrice Gallais; Olivier Pible; Jean-Charles Gaillard; Duarte Gouveia; Hélène Batina; Niza Bazaline; Sylvie Ruat; Karen Culotta; Guylaine Miotello; Stéphanie Debroas; Marie-Anne Roncato; Gérard Steinmetz; Charlotte Foissard; Anne Desplan; Béatrice Alpha-Bazin; Christine Almunia; Fabienne Gas; Laurent Bellanger; Jean Armengaud
Title: Shotgun proteomics of SARS-CoV-2 infected cells and its application to the optimisation of whole viral particle antigen production for vaccines Document date: 2020_4_17
ID: kd02dehk_2
Snippet: Based on the speed at which the outbreak of COVID-19 has developed, SARS-CoV-2 appears to spread easily in the human population. The reproductive number (R0) of the virus is currently thought to be around 3, suggesting the potential for sustained human-to-human transmission that appears to be through respiratory droplets and potentially a fecal-oral route [4] . In this pandemic situation, one of the outstanding questions concerns the possibility .....
Document: Based on the speed at which the outbreak of COVID-19 has developed, SARS-CoV-2 appears to spread easily in the human population. The reproductive number (R0) of the virus is currently thought to be around 3, suggesting the potential for sustained human-to-human transmission that appears to be through respiratory droplets and potentially a fecal-oral route [4] . In this pandemic situation, one of the outstanding questions concerns the possibility to contain the spread of SARS-CoV-2 and its persistence in the human population. Social distancing policy, lock-down and other containment measures have been worldwide implemented to slow down the spread. Current roadmaps to lifting the restrictions rely on the deployment of effective diagnostics, therapies, and eventually on the development of an effective vaccine.
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