Selected article for: "cytokine release and viral infection"

Author: Ryan M. Carey; Jenna R. Freund; Benjamin M. Hariri; Nithin D. Adappa; James N. Palmer; Robert J. Lee
Title: Altered polarization of PAR-2 signaling during airway epithelial remodeling
  • Document date: 2020_1_9
  • ID: 8iet67u3_48
    Snippet: RPMI 2650 cells were proposed as a model of nasal permeability for drug transport studies 62, 63 and cytokine release in allergy 64 or viral infection. 65 Our data here suggest that RPMI 2650 PAR-2 polarization is similar to squamous epithelial cells but not the same as welldifferentiated ciliated cells, so interpretation of RPMI 2650 studies should be done cautiously......
    Document: RPMI 2650 cells were proposed as a model of nasal permeability for drug transport studies 62, 63 and cytokine release in allergy 64 or viral infection. 65 Our data here suggest that RPMI 2650 PAR-2 polarization is similar to squamous epithelial cells but not the same as welldifferentiated ciliated cells, so interpretation of RPMI 2650 studies should be done cautiously.

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