Selected article for: "vaccinia virus and VACV vaccinia virus"
Author: Al Ali, Sally; Baldanta, Sara; Fernández-Escobar, Mercedes; Guerra, Susana
Title: Use of Reporter Genes in the Generation of Vaccinia Virus-Derived Vectors
  • Cord-id: fuz8r3vj
  • Document date: 2016_5_21
    • ID: fuz8r3vj
    Snippet: Vaccinia virus (VACV) is one of the most extensively-studied viruses of the Poxviridae family. It is easy to genetically modify, so it has become a key tool for many applications. In this context, reporter genes facilitate the study of the role of foreign genes introduced into the genome of VACV. In this review, we describe the type of reporter genes that have been used to generate reporter-expressing VACV and the applications of the recombinant viruses obtained. Reporter-expressing VACV are cur
    Document: Vaccinia virus (VACV) is one of the most extensively-studied viruses of the Poxviridae family. It is easy to genetically modify, so it has become a key tool for many applications. In this context, reporter genes facilitate the study of the role of foreign genes introduced into the genome of VACV. In this review, we describe the type of reporter genes that have been used to generate reporter-expressing VACV and the applications of the recombinant viruses obtained. Reporter-expressing VACV are currently employed in basic and immunology research, in the development of vaccines and cancer treatment.

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