Author: Morgan, Camille E.; Rimland, Casey A.; Bell, Griffin J.; Kim, Min K.; Hedrick, Tanner; Marx, Ashley; Bramson, Brian; Swygard, Heidi; Napravnik, Sonia; Schmitz, John L.; Carson, Shannon S.; Fischer, William A.; Eron, Joseph J.; Gay, Cynthia L.; Parr, Jonathan B.
Title: Rapid analysis of local data to inform off-label tocilizumab use early in the COVID-19 pandemic Cord-id: h2rh5bjl Document date: 2021_9_9
ID: h2rh5bjl
Snippet: The interleukin-6 receptor antagonist tocilizumab became widely used early in the coronavirus disease 2019 (COVID-19) pandemic based on small observational studies that suggested clinical benefit in COVID-19 patients with a hyperinflammatory state. To inform our local treatment algorithms in the absence of randomized clinical trial results, we performed a rapid analysis of the first 11 hospitalized COVID-19 patients treated with tocilizumab at our academic medical center. We report their early c
Document: The interleukin-6 receptor antagonist tocilizumab became widely used early in the coronavirus disease 2019 (COVID-19) pandemic based on small observational studies that suggested clinical benefit in COVID-19 patients with a hyperinflammatory state. To inform our local treatment algorithms in the absence of randomized clinical trial results, we performed a rapid analysis of the first 11 hospitalized COVID-19 patients treated with tocilizumab at our academic medical center. We report their early clinical outcomes and describe the process by which we assembled a team of diverse trainees and stakeholders to extract, analyze, and disseminate data during a time of clinical uncertainty.
Search related documents:
Co phrase search for related documents- academic medical system and admission time: 1
- admission time and local practice: 1
- admission time and local treatment: 1, 2
- admission time and low baseline: 1, 2
Co phrase search for related documents, hyperlinks ordered by date