Selected article for: "multicenter phase and open label"

Author: Bersanelli, Melissa; Giannarelli, Diana; Leonetti, Alessandro; Buti, Sebastiano; Tiseo, Marcello; Nouvenne, Antonio; Ticinesi, Andrea; Meschi, Tiziana; Procopio, Giuseppe; Danielli, Riccardo
Title: The right immune-modulation at the right time: thymosin α1 for prevention of severe COVID-19 in cancer patients
  • Cord-id: hg4266q3
  • Document date: 2021_2_4
  • ID: hg4266q3
    Snippet: We presented the rationale for the use of thymosin α1 as prophylaxis of severe COVID-19 in cancer patients undergoing active treatment, constituting the background for the PROTHYMOS study, a prospective, multicenter, open-label, Phase II randomized study, currently in its start-up phase (Eudract no. 2020-006020-13). We aim to offer new hope for this incurable disease, especially to frail patient population, such as patients with cancer. The hypothesis of an effective prophylactic approach to CO
    Document: We presented the rationale for the use of thymosin α1 as prophylaxis of severe COVID-19 in cancer patients undergoing active treatment, constituting the background for the PROTHYMOS study, a prospective, multicenter, open-label, Phase II randomized study, currently in its start-up phase (Eudract no. 2020-006020-13). We aim to offer new hope for this incurable disease, especially to frail patient population, such as patients with cancer. The hypothesis of an effective prophylactic approach to COVID-19 would have immediate clinical relevance, especially given the lack of curative approaches. Moreover, in the ‘COVID-19 vaccine race era’ both clinical and biological results coming from the PROTHYMOS trials could even support the rationale for future combinatorial approaches, trying to rise vaccine efficacy in frail individuals.

    Search related documents:
    Co phrase search for related documents
    • aberrant response and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32
    • aberrant response and adaptive immune response: 1, 2
    • aberrant response and adaptive immune system: 1, 2
    • aberrant response and adaptive innate: 1, 2, 3, 4
    • aberrant response and adaptive innate immunity: 1
    • aberrant response and lung tissue: 1, 2, 3
    • action exact mechanism and acute respiratory syndrome: 1, 2, 3