Selected article for: "cluster analysis and MHC class ii"
Author: Bishajit Sarkar; Md. Asad Ullah; Fatema Tuz Johora; Masuma Afrin Taniya; Yusha Araf
Title: The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against COVID-19
  • Document date: 2020_2_11
    • ID: 7vrm081c_88
    Snippet: The cluster analysis of the MHC alleles which may interact with the selected epitopes during the immune response, showed quite good interaction with each other. Next the 3D structures of the selected epitopes were generated for peptide-protein docking study. The docking was carried out . CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https:/.....
    Document: The cluster analysis of the MHC alleles which may interact with the selected epitopes during the immune response, showed quite good interaction with each other. Next the 3D structures of the selected epitopes were generated for peptide-protein docking study. The docking was carried out . CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.05.935072 doi: bioRxiv preprint to find out whether all the epitopes had the capability to bind with their respective MHC class-I and MHC class-II alleles. Since all the epitopes generated quite good docking scores, it can be concluded that, all of them had the capability to bind with their respective targets and induce potential immune response. However, among the selected epitopes, QLESKMSGK, LIRQGTDYKHWP, GVLTESNKK and TSNFRVQPTESI generated the best docking scores.

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