Author: Tian, Dandan; Sun, YanHong; Zhou, JianMing; Ye, Qing
Title: The global epidemic of SARS-CoV-2 variants and their mutational immune escape. Cord-id: ith5vl79 Document date: 2021_10_5
ID: ith5vl79
Snippet: During the COVID-19 pandemic, genetic variants of SARS-CoV-2 have been emerging and spreading around the world. Several SARS-CoV-2 endemic variants were found in United Kingdom, South Africa, Japan, and India between 2020 and Apr-2021. Studies have shown that many SARS-CoV-2 variants are more infectious than early wild strain and produce immune escape. These SARS-CoV-2 variants have brought new challenges to the prevention and control of COVID-19. This review summarizes and analyzes the biologic
Document: During the COVID-19 pandemic, genetic variants of SARS-CoV-2 have been emerging and spreading around the world. Several SARS-CoV-2 endemic variants were found in United Kingdom, South Africa, Japan, and India between 2020 and Apr-2021. Studies have shown that many SARS-CoV-2 variants are more infectious than early wild strain and produce immune escape. These SARS-CoV-2 variants have brought new challenges to the prevention and control of COVID-19. This review summarizes and analyzes the biological characteristics of different amino acid mutations and the epidemic characteristics and immune escape of different SARS-CoV-2 variants. We hope to provide scientific reference for the monitoring, prevention and control measures of new SARS-CoV-2 variants and the development strategy of the second-generation vaccine. This article is protected by copyright. All rights reserved.
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