Author: Lichao Fan; Chang Liu; Na Li; Huan Liu; Ye Gu; Yongyu Liu; Yu Chen
Title: Medical treatment of 55 patients with COVID-19 from seven cities in northeast China who fully recovered: a single-center, retrospective, observational study Document date: 2020_3_30
ID: hc0za6fh_23
Snippet: In terms of antimicrobial use, the WHO recommends empirical antimicrobial therapy based on the clinical diagnosis. 3 China's COVID-19 Diagnosis and Treatment Plan 2 also emphasizes the avoidance of blind or inappropriate use of antibiotics. Kim et al. 12 found that 38% of their patients . CC-BY-NC 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The WHO .....
Document: In terms of antimicrobial use, the WHO recommends empirical antimicrobial therapy based on the clinical diagnosis. 3 China's COVID-19 Diagnosis and Treatment Plan 2 also emphasizes the avoidance of blind or inappropriate use of antibiotics. Kim et al. 12 found that 38% of their patients . CC-BY-NC 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The WHO does not recommend the systematic use of glucocorticoids for viral pneumonia or concurrent ARDS. 3 China's COVID-19 Diagnosis and Treatment Plan recommends hormones as adjuvant therapy. 2 In the present study, 48 (87·28% ) of the patients did not receive glucocorticoids, while 7 (12·72%) did receive such agents during the rapid progression of their disease to inhibit inflammation and improve oxygenation at a dose of 1-2 mg/kg/day. Treatment was gradually reduced over 5-7 days until discontinuation, and showed no adverse reactions. As such, glucocorticoids appear to be unnecessary for patients with mild manifestations of COVID-19, while their use in treating patients with severe disease is controversial.
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