Author: Huijie Bian; Zhao-Hui Zheng; Ding Wei; Zheng Zhang; Wen-Zhen Kang; Chun-Qiu Hao; Ke Dong; Wen Kang; Jie-Lai Xia; Jin-Lin Miao; Rong-Hua Xie; Bin Wang; Xiu-Xuan Sun; Xiang-Min Yang; Peng Lin; Jie-Jie Geng; Ke Wang; Hong-Yong Cui; Kui Zhang; Xiao-Chun Chen; Hao Tang; Hong Du; Na Yao; Shuang-Shuang Liu; Lin-Na Liu; Zhe Zhang; Zhao-Wei Gao; Gang Nan; Qing-Yi Wang; Jian-Qi Lian; Zhi-Nan Chen; Ping Zhu
Title: Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial Document date: 2020_3_24
ID: 6g34qwer_25
Snippet: The distribution of case severity and discharged cases was analyzed in each group over 28 days follow-up as shown in table 2. The overall improvement rates (defined as the percentage of discharged or improved cases) at days 7, 14, 21, 28 were 17.6% (3/17), 47.1% (8/17), 82.4% (14/17), and 94.1% (16/17) in the meplazumab group, while those were 0% (0/11), 27.3% (3/11), 54.5% (6/11), and 81.8% (9/11) in the control group, respectively. One aggravat.....
Document: The distribution of case severity and discharged cases was analyzed in each group over 28 days follow-up as shown in table 2. The overall improvement rates (defined as the percentage of discharged or improved cases) at days 7, 14, 21, 28 were 17.6% (3/17), 47.1% (8/17), 82.4% (14/17), and 94.1% (16/17) in the meplazumab group, while those were 0% (0/11), 27.3% (3/11), 54.5% (6/11), and 81.8% (9/11) in the control group, respectively. One aggravating case was observed in control group at day 7. At the end of observation (day 28), both groups showed significant improvement compared to baseline (p<0.001 for both meplazumab and control).
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