Selected article for: "cellular receptor and entry mechanism"
Author: Hirano, Toshio; Murakami, Masaaki
Title: COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome
  • Cord-id: ky0pva8y
  • Document date: 2020_4_22
    • ID: ky0pva8y
    Snippet: Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic target via the IL-6-STAT3 axis.
    Document: Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic target via the IL-6-STAT3 axis.

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