Author: Lemke, Greg; Silverman, Gregg J.
Title: Blood clots and TAM receptor signalling in COVID-19 pathogenesis Cord-id: l3rq1er3 Document date: 2020_6_2
ID: l3rq1er3
Snippet: We suggest that the exuberant blood clotting and immune hyper-reaction seen in patients with COVID-19 may be exacerbated by depletion of the same regulator. This agent is protein S, which is both an anticoagulant in the blood coagulation cascade and an activating ligand for the immunosuppressive TAM family of receptor tyrosine kinases.
Document: We suggest that the exuberant blood clotting and immune hyper-reaction seen in patients with COVID-19 may be exacerbated by depletion of the same regulator. This agent is protein S, which is both an anticoagulant in the blood coagulation cascade and an activating ligand for the immunosuppressive TAM family of receptor tyrosine kinases.
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