Selected article for: "fatal outcome and mild respiratory disease"
Author: Remppis, Jonathan; Ganzenmueller, Tina; Kohns Vasconcelos, Malte; Heinzel, Oliver; Handgretinger, Rupert; Renk, Hanna
Title: A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19
  • Cord-id: lvzi0own
  • Document date: 2021_2_1
    • ID: lvzi0own
    Snippet: BACKGROUND: While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited. METHODS: Prospective, observational study at a tertiary care children’s hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed. RESULTS: Between March and November 2020, 14 patients were admitted with COVID-
    Document: BACKGROUND: While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited. METHODS: Prospective, observational study at a tertiary care children’s hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed. RESULTS: Between March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications. CONCLUSIONS: While COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.

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