Author: Bitto, Niccolò; Tosetti, Giulia; La Mura, Vincenzo; Primignani, Massimo
Title: AB0, von Willebrand factor/Factor VIII and portal vein thrombosis in decompensated cirrhosis: too late to unmask the culprit? Cord-id: m3italy7 Document date: 2020_4_28
ID: m3italy7
Snippet: We read with interest the paper from Scheiner et al., who investigated the influence of AB0 blood group on the risk of portal vein thrombosis (PVT) in patients with cirrhosis and wish to make comments. In the general population, the venous thrombosis risk is 2-4 fold increased in non-0 individuals, likely because of their higher von Willebrand factor (VWF) and factor VIII (FVIII) levels. In cirrhotics, VWF and FVIII are markedly increased.
Document: We read with interest the paper from Scheiner et al., who investigated the influence of AB0 blood group on the risk of portal vein thrombosis (PVT) in patients with cirrhosis and wish to make comments. In the general population, the venous thrombosis risk is 2-4 fold increased in non-0 individuals, likely because of their higher von Willebrand factor (VWF) and factor VIII (FVIII) levels. In cirrhotics, VWF and FVIII are markedly increased.
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