Selected article for: "cell surface and MHC class"
Author: Bishajit Sarkar; Md. Asad Ullah; Fatema Tuz Johora; Masuma Afrin Taniya; Yusha Araf
Title: The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against COVID-19
  • Document date: 2020_2_11
    • ID: 7vrm081c_51
    Snippet: The MHC class-I and MHC class-II epitopes, determined for potential vaccine construction. The IEDB (https://www.iedb.org/) server generates a good number of epitopes. However, based on the antigenicity scores, ten epitopes were selected from the top twenty epitopes because the epitopes generated almost similar AS and percentile scores. Later, the epitopes with high antigenicity, nonallergenicity and non-toxicity were selected for vaccine construc.....
    Document: The MHC class-I and MHC class-II epitopes, determined for potential vaccine construction. The IEDB (https://www.iedb.org/) server generates a good number of epitopes. However, based on the antigenicity scores, ten epitopes were selected from the top twenty epitopes because the epitopes generated almost similar AS and percentile scores. Later, the epitopes with high antigenicity, nonallergenicity and non-toxicity were selected for vaccine construction. The B-cell epitopes were also selected based on their antigenicity, non-allergenicity and length (the sequences with more than 10 amino acids). Table 04 and Table 05 list the potential T-cell epitopes of nucleocapsid phosphoprotein and Table 06 and Table 07 list the potential T-cell epitopes of surface glycoprotein. Table 08 lists the predicted B-cell epitopes of the two proteins and Table 09 lists the epitopes that followed the mentioned criteria and were selected for further analysis and vaccine construction.

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