Selected article for: "expression analysis and SARS cov"
Author: Lulin Zhou; Zubiao Niu; Xiaoyi Jiang; Zhengrong Zhang; You Zheng; Zhongyi Wang; Yichao Zhu; Lihua Gao; Xiaoning Wang; Qiang Sun
Title: Systemic analysis of tissue cells potentially vulnerable to SARS-CoV-2 infection by the protein-proofed single-cell RNA profiling of ACE2, TMPRSS2 and Furin proteases
  • Document date: 2020_4_10
    • ID: 3btc31kj_43
    Snippet: Previous analysis based solely on the mRNA expression of ACE2 suggested multiple tissue cells as potential targets of the novel coronavirus SARS-CoV-2, including cells from almost every important human system. However, the COVID-19 patients primarily displayed symptoms from respiratory systems, where ACE2 is expressed in a small portion of cells. Even for severely ill patients, the injuries or symptoms in the ACE2-high organs such as kidney and i.....
    Document: Previous analysis based solely on the mRNA expression of ACE2 suggested multiple tissue cells as potential targets of the novel coronavirus SARS-CoV-2, including cells from almost every important human system. However, the COVID-19 patients primarily displayed symptoms from respiratory systems, where ACE2 is expressed in a small portion of cells. Even for severely ill patients, the injuries or symptoms in the ACE2-high organs such as kidney and intestinal tract are relatively uncommon, with a rate of 1%-4.3% for acute kidney author/funder. All rights reserved. No reuse allowed without permission.

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