Selected article for: "mutant strain and resident mutant strain"

Author: Joe Pharaon; Chris T. Bauch
Title: The Influence Of Social Behavior On Competition Between Virulent Pathogen Strains
  • Document date: 2018_4_4
  • ID: 6s27v6at_29
    Snippet: It is difficult for both strains to co-exist without imposing ω 1 = 10 5 > ω 2 = 10 4 . If the resident strain 216 is perceived to be ten times more severe, then co-existence is achieved via a transient but very long-term 217 pattern of switching between oscillatory regimes before the system finally converges to an equilibrium of 218 co-existence (Fig 1g) . The system switches between a longer-lived regime with relatively small epidemics of rat.....
    Document: It is difficult for both strains to co-exist without imposing ω 1 = 10 5 > ω 2 = 10 4 . If the resident strain 216 is perceived to be ten times more severe, then co-existence is achieved via a transient but very long-term 217 pattern of switching between oscillatory regimes before the system finally converges to an equilibrium of 218 co-existence (Fig 1g) . The system switches between a longer-lived regime with relatively small epidemics of rate which in turns leads to rapid changes in x. Figure 1h shows the same dynamics as in Figure 1g but on 226 a shorter timescale. 227 We also allowed the perceived severities to be equally high (ω 1 = ω 2 = 10 4 ) and we have increased the 228 efficacies from their baseline values ( 1 = 0.9 and 2 = 0.6) (Figure 1i ). We observe that the mutant strain 229 fails to invade and the prevalence of the resident strain remains relatively close to the initial condition.

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