Author: Xi He; Eric HY Lau; Peng Wu; Xilong Deng; Jian Wang; Xinxin Hao; Yiu Chung Lau; Jessica Y Wong; Yujuan Guan; Xinghua Tan; Xiaoneng Mo; Yanqing Chen; Baolin Liao; Weilie Chen; Fengyu Hu; Qing Zhang; Mingqiu Zhong; Yanrong Wu; Lingzhai Zhao; Fuchun Zhang; Benjamin J Cowling; Fang Li; Gabriel M Leung
Title: Temporal dynamics in viral shedding and transmissibility of COVID-19 Document date: 2020_3_18
ID: eflwztji_1
Snippet: variation can be summarized by the incubation period distribution and the serial interval distribution respectively. If the observed mean serial interval is shorter than the observed mean incubation period, this indicates that a significant portion of transmission may have occurred before infected persons have developed symptoms. A large proportion of presymptomatic transmission would likely reduce the effectiveness of control or preventive measu.....
Document: variation can be summarized by the incubation period distribution and the serial interval distribution respectively. If the observed mean serial interval is shorter than the observed mean incubation period, this indicates that a significant portion of transmission may have occurred before infected persons have developed symptoms. A large proportion of presymptomatic transmission would likely reduce the effectiveness of control or preventive measures that are directly or indirectly initiated by symptom onset, such as isolation, contact tracing for quarantine, and enhanced hygiene or use of face masks for symptomatic persons. Failing to consider pre-symptomatic transmission would likely overestimate the effect of such measures when devising control strategies.
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