Author: Derrick Deming; Karen Lee; Tracey McSherry; Ronnie R. Wei; Tim Edmunds; Scott C. Garman
Title: The molecular basis for Pompe disease revealed by the structure of human acid a-glucosidase Document date: 2017_11_1
ID: ey4c74az_1
Snippet: Introduction encompasses residues 347-726 and has the characteristic (β/α) 8 topology found in the catalytic 109 domain of family 31 glycoside hydrolases. C-terminal to the catalytic (β/α) 8 domain, the GAA 110 structure contains two additional β-sandwich domains. Domain C1 spans residues 727-820 and 111 is composed of seven antiparallel β-strands in 5-and 2-stranded β-sheets. The C2 domain has 112 a β-sandwich topology and is composed of.....
Document: Introduction encompasses residues 347-726 and has the characteristic (β/α) 8 topology found in the catalytic 109 domain of family 31 glycoside hydrolases. C-terminal to the catalytic (β/α) 8 domain, the GAA 110 structure contains two additional β-sandwich domains. Domain C1 spans residues 727-820 and 111 is composed of seven antiparallel β-strands in 5-and 2-stranded β-sheets. The C2 domain has 112 a β-sandwich topology and is composed of 10 β-strands in two 5-stranded β-sheets, with two 113 small α-helices inserted ( Fig. 1 and Fig. 1 supplement B) . and the surface-exposed C938 and C952 in the C2 domain (Fig. 1) .
Search related documents:
Co phrase search for related documents- glycoside hydrolase and β sandwich: 1
- glycoside hydrolase and β sandwich domain: 1
- α helix and β β sheet strand: 1
- α helix and β sandwich: 1, 2, 3
- α helix and β sheet: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30
- α helix and β sheet strand: 1
- α helix and small α helix: 1, 2, 3
- β β sheet strand and β sheet: 1, 2
- β β sheet strand and β sheet strand: 1, 2
- β sheet and seven antiparallel: 1
Co phrase search for related documents, hyperlinks ordered by date