Selected article for: "aerosol inhalation and respiratory tract"
Author: Sosnowski, Tomasz R.
Title: Inhaled aerosols: their role in COVID-19 transmission including biophysical interactions in the lungs
  • Cord-id: q90442xb
  • Document date: 2021_3_24
    • ID: q90442xb
    Snippet: The high rate of spreading of COVID-19 is attributed to airborne particles exhaled by infected but often asymptomatic individuals. In this review the role of aerosols in SARS-CoV-2 coronavirus transmission is discussed from the bio-physical perspective. The essential properties of the coronavirus virus transported inside aerosol droplets, their successive inhalation, and size-dependent deposition in the respiratory system are highlighted. The importance of face covers (respirators and masks) in
    Document: The high rate of spreading of COVID-19 is attributed to airborne particles exhaled by infected but often asymptomatic individuals. In this review the role of aerosols in SARS-CoV-2 coronavirus transmission is discussed from the bio-physical perspective. The essential properties of the coronavirus virus transported inside aerosol droplets, their successive inhalation, and size-dependent deposition in the respiratory system are highlighted. The importance of face covers (respirators and masks) in the reduction of aerosol spreading is analyzed. Finally, the discussion of the physicochemical phenomena upon coronavirus enter to surface of lung liquids (bronchial mucus and pulmonary surfactant) is presented with a focus on a possible role of interfacial phenomena in pulmonary alveoli. Information given in this review should be important in understanding the essential biophysical conditions of COVID-19 infection via aerosol route as a prerequisite for effective strategies of respiratory tract protection and, possibly, indications for future treatments of the disease.

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