Document: INTRODUCTION: The COVID-19 pandemic has caused major impacts to social and financial status for many people, including those living in the vulnerable US-Mexico border region. This study examined relationships between changes in sleep and perceived impacts to social and financial stability due to the pandemic. METHODS: Participants were 155 individuals who completed the Nogales Cardiometabolic Health and Sleep (NOCHES) and were contacted about completing a COVID sub-study (95% Hispanic/Latino). Participants were asked if the COVID-19 pandemic was causing them to feel more socially isolated, negatively impacting their finances, causing increased worry about finances, affecting their primary job, causing a job loss, and impacting their belief life will one day return to normal. In addition, they were asked to report the degree to which they experienced pandemic-related changes to sleep, including a regularity, overall improvement/worsening, initial and middle-of-the-night insomnia, daytime sleepiness, and napping. Logistic regression analyses were adjusted for age, sex, socioeconomics, and mental health (PHQ4). RESULTS: Those who kept a more regular schedule had lower odds of endorsing isolation (OR=0.32,p<0.0005) and higher odds of believing things will return to normal (OR=1.67,p=0.041). Those whose sleep improved also had lower odds of feeling isolated (OR=0.40,p=0.005). Those with worsened sleep had increased odds of feeling isolated (OR=2.14,p=0.023), experiencing a financial impact (OR=1.85,p=0.016) and increased financial worry (OR=1.71,p=0.033), and lower odds of believing things will return to normal (OR=0.53,p=0.012). More initial insomnia was associated with isolation (OR=3.62,p=0.001), financial impact, (OR=1.89,p=0.015), financial worry (OR=1.87,p=0.016) and job impact (OR=1.95,p=0.010). More middle-of-the-night insomnia was associated with financial worry (OR=1.82,p=0.016) and job impact (OR=1.93,p=0.009). More sleepiness was associated with job loss (OR=1.84,p=0.043). More napping was associated with financial impact (OR=1.89,p=0.017) and worry (OR=1.88,p=0.017), impact to job (OR=1.89,p=0.016) or lost job (OR=1.81,p=0.041), and decreased likelihood of believing things will return to normal (OR=0.45,p=0.003). CONCLUSION: Pandemic-related stress was linked with sleep disturbances. Worse sleep was indicative of increased social isolation, greater financial fears, more job-related impacts and less of a general sense that things would return to normal. SUPPORT (IF ANY): Supported by T32HL007249, R01MD011600, R01DA051321
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