Author: Lei Lei; Hongbo Qian; Xiaofeng Yang; Xiaobo Zhou; Xingzhe Zhang; Dan Zhang; Tongxin Dai; Rui Guo; Lin Shi; Yanbin Cheng; Baojun Zhang; Jinsong Hu Hu; Yaling Guo
Title: The phenotypic changes of ?d T cells in COVID-19 patients Document date: 2020_4_7
ID: 5ekdfers_8
Snippet: Among innate immune cells, γ δ T cells proliferate rapidly and respond to pathogens by inducing apoptosis, mediating antigen presentation and immune regulation [10] . In healthy adult humans, γ δ T cells represent 1%-10% of the total circulating lymphocytes, predominately displaying the CD4 and CD8 double negative phenotype [11] . However, in some cases, a fraction of γ δ T cells can express either CD4 or CD8 [12] [13] [14] . γ δ T cells .....
Document: Among innate immune cells, γ δ T cells proliferate rapidly and respond to pathogens by inducing apoptosis, mediating antigen presentation and immune regulation [10] . In healthy adult humans, γ δ T cells represent 1%-10% of the total circulating lymphocytes, predominately displaying the CD4 and CD8 double negative phenotype [11] . However, in some cases, a fraction of γ δ T cells can express either CD4 or CD8 [12] [13] [14] . γ δ T cells do not recognize classical peptide antigens, their TCRs are non-MHC restricted and they can respond to pathogen-associated molecular patterns and produce cytokines in the All rights reserved. No reuse allowed without permission.
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