Author: Kai Duan; Bende Liu; Cesheng Li; Huajun Zhang; Ting Yu; Jieming Qu; Min Zhou; Li Chen; Shengli Meng; Yong Hu; Cheng Peng; Mingchao Yuan; Jinyan Huang; Zejun Wang; Jianhong Yu; Xiaoxiao Gao; Dan Wang; Xiaoqi Yu; Li Li; Jiayou Zhang; Xiao Wu; Bei Li; Yanping Yu; Wei Chen; Yan Peng; Yeqin Hu; Lianzhen Lin; Xuefei Liu; Shihe Huang; Zhijun Zhou; Lianghao Zhang; Yue Wang; Zhi Zhang; Kun Deng; Zhiwu Xia; Qin Gong; Wei Zhang; Xiaobei Zheng; Ying Liu; Huichuan Yang; Dongbo Zhou; Ding Yu; Jifeng Hou; Zhengli Shi; Saijuan Chen; Zhu Chen; Xin-xin Zhang; Xiaoming Yang
Title: The feasibility of convalescent plasma therapy in severe COVID-19 patients: a pilot study Document date: 2020_3_23
ID: 8znnq0rh_16
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03. 16.20036145 doi: medRxiv preprint high-flow nasal cannula oxygenation, and two received conventional low-flow nasal cannula oxygenation. After treatmentwith CP, two patients were weaned from mechanical ventilation to high-flow nasal cannula and one patient discontinued high flow nasal cannula. Besides, in one patient treated with convent.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03. 16.20036145 doi: medRxiv preprint high-flow nasal cannula oxygenation, and two received conventional low-flow nasal cannula oxygenation. After treatmentwith CP, two patients were weaned from mechanical ventilation to high-flow nasal cannula and one patient discontinued high flow nasal cannula. Besides, in one patient treated with conventional nasal cannula oxygenation, continuous oxygenation was shifted to intermittent one ( Table 2) . Table 3 ). The total bilirubin (median: 12.40 μmol/L vs. 13.98 μmol/L) remained unchanged except an obvious increment in patient 1 (Fig. 2 ). An increase of SaO2 (median:93.00% vs. 96.00%), a measurement constantly performed in most patients in our trial, was found, which could indicaterecovering lung function.This temporal relationship was notable despite the provision of maximal supportive care and antiviral agents.
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