Author: Feria Hikmet; Loren Méar; Mathias Uhlén; Cecilia Lindskog
Title: The protein expression profile of ACE2 in human tissues Document date: 2020_4_3
ID: 4fz6iqwy_6
Snippet: ACE2 is a carboxypeptidase negatively regulating the renin-angiotensin system (RAS), which can induce vasodilation by cleaving angiotensin II. The protein was identified in 2000 as a homolog to ACE 3 and due to the importance of ACE in cardiovascular disease, and the use of ACE inhibitors for treatment of high blood pressure and heart failure, there has been a large interest in understanding the function and expression of ACE2 in various human or.....
Document: ACE2 is a carboxypeptidase negatively regulating the renin-angiotensin system (RAS), which can induce vasodilation by cleaving angiotensin II. The protein was identified in 2000 as a homolog to ACE 3 and due to the importance of ACE in cardiovascular disease, and the use of ACE inhibitors for treatment of high blood pressure and heart failure, there has been a large interest in understanding the function and expression of ACE2 in various human organs. In Figure 1 , a summary of the expression levels in a selection of different organs is shown, based on publicly available datasets on both transcriptomic and proteomic levels.
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