Selected article for: "crude cfr and Hubei province"
Author: Julien Riou; Anthony Hauser; Michel J Counotte; Christian L Althaus
Title: Adjusted age-specific case fatality ratio during the COVID-19 epidemic in Hubei, China, January and February 2020
  • Document date: 2020_3_6
    • ID: mrsya6wz_42
    Snippet: We developed a mechanistic approach to correct the crude CFR for bias due to right-censoring and preferential ascertainment and provide adjusted estimates of mortality due to SARS-CoV-2 infection by age group and according to symptom status. The adjusted estimates of mortality in Hubei province, China and northern Italy were similar, and higher than the crude CFR, suggesting that, in these settings at these times, right-censoring is a more import.....
    Document: We developed a mechanistic approach to correct the crude CFR for bias due to right-censoring and preferential ascertainment and provide adjusted estimates of mortality due to SARS-CoV-2 infection by age group and according to symptom status. The adjusted estimates of mortality in Hubei province, China and northern Italy were similar, and higher than the crude CFR, suggesting that, in these settings at these times, right-censoring is a more important source of bias than preferential ascertainment. The steep increase in mortality among people aged 60 years and older, reaching extremely high values in people aged 80 years and older is of concern. While specific to the situation in Hubei, China and northern Italy during these periods, these findings will help the mitigation efforts and planning of resources as other regions prepare for SARS-CoV-2 epidemics.

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