Author: Berger, J.; Volc, S.
Title: Autoantibodies in Covidâ€19 – a model for viral induced autoimmunity Cord-id: vr7ov495 Document date: 2021_6_11
ID: vr7ov495
Snippet: the novel Coronavirus SARS-CoV-2 is suspected of acting as a trigger for autoimmune diseases and the production of autoantibodies. Retinoic acid-inducible gene (RIG)-I-like receptors (RLR), including melanoma differentiation-associated protein 5 (MDA5) and RIG-I, recognize the double-strand (ds) virus RNA and induce the production of Type I interferon (Type I IFN) as well as pro-inflammatory cytokines like Interleukin (IL)-6.
Document: the novel Coronavirus SARS-CoV-2 is suspected of acting as a trigger for autoimmune diseases and the production of autoantibodies. Retinoic acid-inducible gene (RIG)-I-like receptors (RLR), including melanoma differentiation-associated protein 5 (MDA5) and RIG-I, recognize the double-strand (ds) virus RNA and induce the production of Type I interferon (Type I IFN) as well as pro-inflammatory cytokines like Interleukin (IL)-6.
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