Author: Arachchillage, Deepa J; Remmington, Christopher; Rosenberg, Alex; Xu, Tina; Passariello, Maurizio; Hall, Donna; Laffan, A Mike; Patel, Brijesh V
Title: Anticoagulation with Argatroban in patients with acute antithrombin deficiency in severe COVID â€19 Cord-id: wnpiptly Document date: 2020_6_9
ID: wnpiptly
Snippet: COVIDâ€19 is a highly prothrombotic disease, frequently requiring anticoagulation for prevention or treatment of thrombosis and to enable organ support (Bikdeli, Madhavan et al. 2020). The reported incidence of thrombosis in patients with COVIDâ€19 varies considerably depending on anticoagulant regimen, severity of disease and additional risk factors such as central lines. The most commonly used inâ€hospital anticoagulants, unfractionated heparin (UFH) and low molecular weight heparin (LMWH),
Document: COVIDâ€19 is a highly prothrombotic disease, frequently requiring anticoagulation for prevention or treatment of thrombosis and to enable organ support (Bikdeli, Madhavan et al. 2020). The reported incidence of thrombosis in patients with COVIDâ€19 varies considerably depending on anticoagulant regimen, severity of disease and additional risk factors such as central lines. The most commonly used inâ€hospital anticoagulants, unfractionated heparin (UFH) and low molecular weight heparin (LMWH), require antithrombin (AT) to exert their anticoagulant effect (Bussey and Francis 2004). Therefore, AT deficiency can result in failure achieve adequate anticoagulation with UFH or LMWH at usual doses.
Search related documents:
Co phrase search for related documents- acute anticoagulation and lmwh weight heparin: 1
- acute anticoagulation and low molecular lmwh weight heparin: 1
- adequate anticoagulation achieve and lmwh weight heparin: 1
- adequate anticoagulation achieve and low molecular lmwh weight heparin: 1
- adequate anticoagulation and lmwh weight heparin: 1, 2
- adequate anticoagulation and low molecular lmwh weight heparin: 1, 2
- lmwh weight heparin and low molecular lmwh weight heparin: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date