Author: Kwang Su Kim; Keisuke Ejima; Yusuke Ito; Shoya Iwanami; Hirofumi Ohashi; Yoshiki Koizumi; Yusuke Asai; Shinji Nakaoka; Koichi Watashi; Robin N Thompson; Shingo Iwami
Title: Modelling SARS-CoV-2 Dynamics: Implications for Therapy Document date: 2020_3_27
ID: 09r4d3nu_41
Snippet: By utilising our novel mathematical model and the estimated parameter 276 values, we investigated the antiviral effects of unlicensed but developing (promising) 277 drugs with the following different mechanisms of action, depending on inhibition rates 278 and timings of therapy initiation: (i) blocking de novo infection (e.g. via human 279 neutralising antibodies, viral entry-inhibitors and antibody levels raised by 280.....
Document: By utilising our novel mathematical model and the estimated parameter 276 values, we investigated the antiviral effects of unlicensed but developing (promising) 277 drugs with the following different mechanisms of action, depending on inhibition rates 278 and timings of therapy initiation: (i) blocking de novo infection (e.g. via human 279 neutralising antibodies, viral entry-inhibitors and antibody levels raised by 280
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