Selected article for: "envelope glycoprotein and genome size"
Author: Umar Faruq Chowdhury; Mohammad Umer Sharif Shohan; Kazi Injamamul Hoque; Mirza Ashikul Beg; Mohammad Ali Moni; Mohammad Kawsar Sharif Siam
Title: A Computational Approach to Design Potential siRNA Molecules as a Prospective Tool for Silencing Nucleocapsid Phosphoprotein and Surface Glycoprotein Gene of SARS-CoV-2
  • Document date: 2020_4_12
    • ID: exoc6xvt_3
    Snippet: Gammacoronavirus, and Deltacoronavirus [12] . The first two genera generally infect mammals, 56 while the last two mostly cause disease in birds. The genome size of coronaviruses ranges between 57 approximately 26-32 kb and includes about 6 to 11 open reading frames (ORFs) [13] . Nucleocapsid 58 protein (N), small envelope protein (E), spike surface glycoprotein (S) and matrix protein (M) are 59 the four major structural proteins of coronavirus a.....
    Document: Gammacoronavirus, and Deltacoronavirus [12] . The first two genera generally infect mammals, 56 while the last two mostly cause disease in birds. The genome size of coronaviruses ranges between 57 approximately 26-32 kb and includes about 6 to 11 open reading frames (ORFs) [13] . Nucleocapsid 58 protein (N), small envelope protein (E), spike surface glycoprotein (S) and matrix protein (M) are 59 the four major structural proteins of coronavirus and all of which are essential to produce a 60 structurally complete virus [14, 15] . The nucleocapsid protein (N) is a multifunctional protein 61 comprising three distinct and highly conserved domains: two structural and independently folded 62 structural regions, namely the N terminal domain and C-terminal domain, which are separated by a 63

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