Author: Shaghee, Foaad; Nafakhi, Hussein; Alareedh, Mohammed; Nafakhi, Ahmed; Alâ€Buthabhak, Karrar
Title: ECG markers of malignant arrhythmias and inâ€hospital outcome of COVIDâ€19 pneumonia Cord-id: xw44w868 Document date: 2021_1_24
ID: xw44w868
Snippet: BACKGROUND: ECG abnormalities associated with COVIDâ€19 pneumonia and adverse outcome are undefined and poorly described in prior studies. OBJECTIVES: To assess the predictive role of baseline ECG markers of increased risk of malignant arrhythmias and cardiac death for adverse inâ€hospital outcomes. PATIENTS AND METHODS: A retrospective study included 93 patients of newly diagnosed COVIDâ€19 with features consistent with pneumonia who were admitted to the hospital from August 20 to September
Document: BACKGROUND: ECG abnormalities associated with COVIDâ€19 pneumonia and adverse outcome are undefined and poorly described in prior studies. OBJECTIVES: To assess the predictive role of baseline ECG markers of increased risk of malignant arrhythmias and cardiac death for adverse inâ€hospital outcomes. PATIENTS AND METHODS: A retrospective study included 93 patients of newly diagnosed COVIDâ€19 with features consistent with pneumonia who were admitted to the hospital from August 20 to September 20, 2020. The main outcomes were defined as receiving mechanical ventilation, inâ€hospital cardiac arrest, length of ICU stay, and degree of lung damage according to computed tomography (CT) score. RESULTS: Increased QTc (QT corrected) interval, Tpâ€e (T from peak to end) interval, and transmural dispersion of repolarization (TDR) were independent predictors of prolonged ICU stay (P < .0001) after adjustment for baseline clinical characteristics. Increasing age (P < .0001) followed by increased QTc interval (P = .02) and history of chronic lung disease (P = .04) were independent predictors of extensive lung damage. The independent predictors for inâ€hospital cardiac arrest were increased QTc (P = .02) followed by increasing age (P = .04) and increased Tpâ€e interval (P = .04). CONCLUSION: Repolarization abnormalities on baseline ECG may be useful prognostic markers in patients with COVIDâ€19 pneumonia.
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