Selected article for: "body trs and RNA synthesis"
Author: Hazel Stewart; Katherine Brown; Adam M. Dinan; Nerea Irigoyen; Eric J. Snijder; Andrew E. Firth
Title: The transcriptional and translational landscape of equine torovirus
  • Document date: 2018_4_7
    • ID: mozfm5ds_9
    Snippet: Here we describe the first high-resolution analysis of viral transcription during 114 infection by EToV, which is one of the few toroviruses that can be propagated in cell 115 culture (13, 14) . RNA sequencing (RNA-seq) confirmed previous reports that EToV 116 utilises a unique combination of both discontinuous and non-discontinuous RNA 117 synthesis to generate its repertoire of sgRNAs. Strikingly, we also identified a small 118 proportion of ch.....
    Document: Here we describe the first high-resolution analysis of viral transcription during 114 infection by EToV, which is one of the few toroviruses that can be propagated in cell 115 culture (13, 14) . RNA sequencing (RNA-seq) confirmed previous reports that EToV 116 utilises a unique combination of both discontinuous and non-discontinuous RNA 117 synthesis to generate its repertoire of sgRNAs. Strikingly, we also identified a small 118 proportion of chimaeric transcripts spanning from the leader to the body TRS of the 119 N protein gene, indicating that discontinuous and non-discontinuous mechanisms 120 compete in this location. We also identified numerous locations across the genome 121

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