Author: Li, Jiacheng; Ma, Xiaoliang; Guo, Shuai; Hou, Chengyu; Shi, Liping; Zhang, Hongchi; Zheng, Bing; Liao, Chenchen; Yang, Lin; Ye, Lin; He, Xiaodong
Title: A Hydrophobicâ€Interactionâ€Based Mechanism Triggers Docking between the SARSâ€CoVâ€2 Spike and Angiotensinâ€Converting Enzyme 2 (Global Challenges 12/2020) Cord-id: 2ftedgpa Document date: 2020_12_3
ID: 2ftedgpa
Snippet: In article number 2000067 Lin Yang and coâ€workers find that the hydrophobic interaction between the SARSâ€CoVâ€2 spike protein and the ACE2 protein is significantly greater than that between the SARSâ€CoV spike protein and the ACE2 protein. At the docking site, the hydrophobic portions of the hydrophilic side chains of SARSâ€CoVâ€2 S are found to be involved in the hydrophobic interaction between the SARSâ€CoVâ€2 spike protein and ACE2. [Image: see text]
Document: In article number 2000067 Lin Yang and coâ€workers find that the hydrophobic interaction between the SARSâ€CoVâ€2 spike protein and the ACE2 protein is significantly greater than that between the SARSâ€CoV spike protein and the ACE2 protein. At the docking site, the hydrophobic portions of the hydrophilic side chains of SARSâ€CoVâ€2 S are found to be involved in the hydrophobic interaction between the SARSâ€CoVâ€2 spike protein and ACE2. [Image: see text]
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