Author: Leonardo Setti; Fabrizio Passarini; Gianluigi De Gennaro; Pierluigi Barbieri; Maria Grazia Perrone; Andrea Piazzalunga; Massimo Borelli; Jolanda Palmisani; Alessia Di Gilio; PRISCO PISCITELLI; Alessandro Miani
Title: The Potential role of Particulate Matter in the Spreading of COVID-19 in Northern Italy: First Evidence-based Research Hypotheses Document date: 2020_4_17
ID: hu6iwoab_1
Snippet: Severe acute respiratory syndrome known as COVID-19 disease (due to SARS-CoV-2 virus), is recognized to spread via respiratory droplets and close contacts [1] . However, this unique transmission model does not seem to explain properly the different spread observed in Italy from February 24th, 2020 to March 13rd, 2020. The huge virulence of COVID19 in the Po Valley is not comparable to the milder contagiousness observed in the central-southern reg.....
Document: Severe acute respiratory syndrome known as COVID-19 disease (due to SARS-CoV-2 virus), is recognized to spread via respiratory droplets and close contacts [1] . However, this unique transmission model does not seem to explain properly the different spread observed in Italy from February 24th, 2020 to March 13rd, 2020. The huge virulence of COVID19 in the Po Valley is not comparable to the milder contagiousness observed in the central-southern regions. Demographic factors related to the ageing of the population and the possibility of infection without clinical symptoms for a quite long time -associated with the high rate of asymptomatic people that characterize COVID-19, estimated in 50-75% of infections -may only partially explain the fast spreading of the virus in Lombardy and Northern Italy [2, 3] . Cai et al (2020) reported different incubation periods in patient(s) infected in Wuhan [4] , but an epidemic model based only on respiratory droplets and close contact could not fully explain the regional differences in the spreading of the recent severe acute respiratory syndrome COVID-19 in Italy, which was fast and dramatic only in Lombardy and Po Valley.
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