Editorial: The Crossroads Between Immunological Disorders and Neuropsychiatric Diseases. A Case for Schizophrenia

Sánchez-Ramón, Silvia; Faure, Florence; Jolles, Stephen; Leboyer, Marion; Tremblay, Marie-Ève

First episode psychosis patients were further grouped based on their presence or absence of mood disorder. [...]Maes and Anderson close this Research topic with a thought-provoking opinion article on the “false conceptualizations” of SZ in the pursuit of a holistic view of the disorder and propose a new nomothetic network-model framework based on machine learning methods to track “evidence based” progress through model group-based classification across stages. Silvia Sánchez-Ramón1*, Florence Faure2, Stephen Jolles3, Marion Leboyer4,5 and Marie-Ève Tremblay6,7,8,9,10 * 1Department of Clinical Immunology, Instituto de Medicina de Laboratorio and Instituto de Investigación Sanitaria San Carlos, Hospital Clínico San Carlos, Madrid, Spain * 2INSERM U932, PSL Research University, Institut Curie, Paris, France * 3Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom * 4Université Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Créteil, France * 5AP-HP, Hôpitaux Universitaires H. Mondor, DMU IMPACT, FHU ADAPT, Créteil, France * 6Division of Medical Sciences, University of Victoria, Victoria, BC, Canada * 7Axe Neurosciences, Centre de Recherche du Centre Hospitalier de l'Université de Montréal de Québec-Université Laval, Québec, QC, Canada * 8Department of Molecular Medicine, Faculty of Medicine, Université Laval, Québec, QC, Canada * 9Neurology and Neurosurgery Department, McGill University, Montréal, QC, Canada * 10Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada