Selected article for: "incubation period and sensitivity analysis"
Author: Chentong Li; Jinhu Xu; Jiawei Liu; Yicang Zhou
Title: The within-host viral kinetics of SARS-CoV-2
  • Document date: 2020_3_2
    • ID: 1yka7ej9_20
    Snippet: Based on the chest radiograph data, we estimate the parameters and basic reproductive number of the model (1). The R 0 of SARS-CoV-2 in host growth is 3.79, which is higher than HCV (2.3, [2] ), but lower than the flu virus (23, [10] ). Comparing the estimated parameters of SARS-CoV-2 with MERS coronavirus, the MERS have a higher virulence to infect the pulmonary epithelial cells (larger R 0 ) and with a small initial value of infected cell. Thes.....
    Document: Based on the chest radiograph data, we estimate the parameters and basic reproductive number of the model (1). The R 0 of SARS-CoV-2 in host growth is 3.79, which is higher than HCV (2.3, [2] ), but lower than the flu virus (23, [10] ). Comparing the estimated parameters of SARS-CoV-2 with MERS coronavirus, the MERS have a higher virulence to infect the pulmonary epithelial cells (larger R 0 ) and with a small initial value of infected cell. These may esplain why the MERS have a higher mortality and smaller incubation period [6, 13] . By the PRCC method, the sensitivity analysis is also done on the R 0 , and the positive correlation of E p (0) with R 0 may give a possible reason why the baby patients are less likely to die of this virus. We also analyze the drug therapy and its effect on the virus growth, and the result illustrates that early medication is effective for treatment.

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