Author: Brizuela, M.; Lenzi, J.; Ulloa Gutierrez, R.; Yassef, O.; Rios Aida, J. A.; del Aguila, O.; arteaga, E.; Campos, F.; Uribe, F.; Parra, A.; Betancur, L.; Gomez-Vargas, J.; Yock, A.; buonsenso, d.
Title: Influence of sex on disease severity in children with COVID-19 and Multisystem Inflammatory Syndrome in Latin America Cord-id: 423486zt Document date: 2021_2_9
ID: 423486zt
Snippet: Data from adult studies how that COVID-19 is more severe in men than women. However, no data are available for the pediatric population. For this reason, we performed this study aiming to understand if sex influenced disease severity and outcomes in a large cohort of latin-american children with COVID-19 and Multisystem Inflammatory Syndrome (MIS-C). We found that a higher percentage of male children developed MIS-C (8.9% vs 5% in females) and died (1.2% and 0.4% in females), although on multiva
Document: Data from adult studies how that COVID-19 is more severe in men than women. However, no data are available for the pediatric population. For this reason, we performed this study aiming to understand if sex influenced disease severity and outcomes in a large cohort of latin-american children with COVID-19 and Multisystem Inflammatory Syndrome (MIS-C). We found that a higher percentage of male children developed MIS-C (8.9% vs 5% in females) and died (1.2% and 0.4% in females), although on multivariate adjusted analyses the only statistically significant difference was found in need of hospitalization, with females less frequently admitted compared with boys (25.6% vs 35.4%). This data are preliminary and need further independent studies to better assess the role of sex.
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