Selected article for: "cell cluster and marker expression"
Author: Lulin Zhou; Zubiao Niu; Xiaoyi Jiang; Zhengrong Zhang; You Zheng; Zhongyi Wang; Yichao Zhu; Lihua Gao; Xiaoning Wang; Qiang Sun
Title: Systemic analysis of tissue cells potentially vulnerable to SARS-CoV-2 infection by the protein-proofed single-cell RNA profiling of ACE2, TMPRSS2 and Furin proteases
  • Document date: 2020_4_10
    • ID: 3btc31kj_15
    Snippet: We applied two strategies to determine cell types. (1) Canonical marker genes were applied to annotate each cluster into known biological cell types. Expression dot plots or heatmaps of the marker genes for each cluster are shown in Figure 3. (2) We used the "Find All Markers" function from R package Seurat to find differentially expressed genes by comparing each cluster of cells with all other cells. Differentially expressed genes in each cluste.....
    Document: We applied two strategies to determine cell types. (1) Canonical marker genes were applied to annotate each cluster into known biological cell types. Expression dot plots or heatmaps of the marker genes for each cluster are shown in Figure 3. (2) We used the "Find All Markers" function from R package Seurat to find differentially expressed genes by comparing each cluster of cells with all other cells. Differentially expressed genes in each cluster were enriched to the cell markers gene sets [40] using the "Cluster Profiler" R package (version3.14.3) [41] to predict the probable cell types.

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