Selected article for: "cell donor and donor cell"
Author: Lulin Zhou; Zubiao Niu; Xiaoyi Jiang; Zhengrong Zhang; You Zheng; Zhongyi Wang; Yichao Zhu; Lihua Gao; Xiaoning Wang; Qiang Sun
Title: Systemic analysis of tissue cells potentially vulnerable to SARS-CoV-2 infection by the protein-proofed single-cell RNA profiling of ACE2, TMPRSS2 and Furin proteases
  • Document date: 2020_4_10
    • ID: 3btc31kj_27
    Snippet: The lung as the pivotal respiratory organ is one of the target organs of SARS-CoV-2. In the lung dataset, 3750 cells from an Asian donor passed stringent quality control and represented 9 cell types. Specifically, we identified alveolar type II (AT2) cells, alveolar type I (AT1) cells, ciliated and club cells, alveolar macrophages, dendritic cells, monocytes, fibroblasts, and endothelial cells. Expression of canonical cell markers for pulmonary c.....
    Document: The lung as the pivotal respiratory organ is one of the target organs of SARS-CoV-2. In the lung dataset, 3750 cells from an Asian donor passed stringent quality control and represented 9 cell types. Specifically, we identified alveolar type II (AT2) cells, alveolar type I (AT1) cells, ciliated and club cells, alveolar macrophages, dendritic cells, monocytes, fibroblasts, and endothelial cells. Expression of canonical cell markers for pulmonary cell types was observed in largely non-overlapping cells, including SFTPC for AT2 cells, AGER for AT1 cells, author/funder. All rights reserved. No reuse allowed without permission.

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