Author: Zhiheng Xu; Jianmeng Zhou; Yongbo Huang; Xuesong Liu; Yonghao Xu; Sibei Chen; Dongdong Liu; Zhimin Lin; Xiaoqing Liu; Yimin Li
Title: The efficacy of convalescent plasma for the treatment of severe influenza Document date: 2020_2_23
ID: 4pe9o59g_45
Snippet: Our analyses suggested that convalescent plasma may not have a clinically relevant impact in reducing the rate of mortality in patients with influenza. We also found non-significant reductions in days in ICU and hospital, and days on mechanical We included 5 high quality RCTs of convalescent plasma and H-IVIG use in severe influenza. The evidence for a reduction in mortality associated with convalescent plasma was strongest for influenza A (H1N1).....
Document: Our analyses suggested that convalescent plasma may not have a clinically relevant impact in reducing the rate of mortality in patients with influenza. We also found non-significant reductions in days in ICU and hospital, and days on mechanical We included 5 high quality RCTs of convalescent plasma and H-IVIG use in severe influenza. The evidence for a reduction in mortality associated with convalescent plasma was strongest for influenza A (H1N1) (17) . But we should interpret this with an appropriate level of caution because of the limited sample size (n=17) and early use (onset within 5 days). In addition, the pooled data of 4 trails (n=567) that All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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