Author: Alisher M Kariev; Michael E Green
Title: The Role of Proton Transport in Gating Current in a Voltage Gated Ion Channel, as Shown by Quantum Calculations Document date: 2018_7_19
ID: cyxdy7hg_4
Snippet: Prior to opening the channel, there is a capacitative current of relatively short duration, the gating current (20) . This is consistent with the motion of positive charges through the VSD of the channel; the potassium channels we are considering have four such domains, plus a central pore domain through which the ionic current passes. The gating current passes through the VSD; the gating charge can be inferred from measurement of the gating curr.....
Document: Prior to opening the channel, there is a capacitative current of relatively short duration, the gating current (20) . This is consistent with the motion of positive charges through the VSD of the channel; the potassium channels we are considering have four such domains, plus a central pore domain through which the ionic current passes. The gating current passes through the VSD; the gating charge can be inferred from measurement of the gating current; this is often done by assuming a single "Boltzmann curve": P o = 1/(1 + exp(-qeV/k B T))
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