Author: D'Aloisio, Rossella; Nasillo, Vincenzo; Gironi, Matteo; Mastropasqua, Rodolfo
Title: Bilateral macular hemorrhage in a patient with COVID-19 Cord-id: czrj1pgb Document date: 2020_10_9
ID: czrj1pgb
Snippet: PURPOSE: We report a case of a patient with a known hereditary spherocytosis who developed a bilateral macular hemorrhage in concurrence with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related respiratory syndrome. OBSERVATIONS: Blood tests showed severe hemolytic anemia. Interestingly, the peripheral blood smear demonstrated a mixed pathogenesis of the hemolytic process (cold-agglutinin-mediated and non-immune-mediated due to spherocytosis). CONCLUSIONS AND IMPORTANCE: We argu
Document: PURPOSE: We report a case of a patient with a known hereditary spherocytosis who developed a bilateral macular hemorrhage in concurrence with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related respiratory syndrome. OBSERVATIONS: Blood tests showed severe hemolytic anemia. Interestingly, the peripheral blood smear demonstrated a mixed pathogenesis of the hemolytic process (cold-agglutinin-mediated and non-immune-mediated due to spherocytosis). CONCLUSIONS AND IMPORTANCE: We argue that SARS-CoV-2 could have triggered the hemolytic process, which led to retinal hemorrhages due to endothelial anoxia from the low oxygen carrying capacity.
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