Author: Michael Zietz; Nicholas P. Tatonetti
Title: Testing the association between blood type and COVID-19 infection, intubation, and death Document date: 2020_4_11
ID: 3xvphg52_18
Snippet: We found that blood groups provide significant additional information on outcomes beyond risk factors. First, we verified that the risk factors (outcome ~ risk factors) provide predictive power compared to intercept-only null models (Table 9 ). Then, we evaluated blood group's effect on COVID-19 outcomes beyond risk factors using analysis of deviance. Specifically, we compared models including both risk factors and blood group (outcome ~ blood gr.....
Document: We found that blood groups provide significant additional information on outcomes beyond risk factors. First, we verified that the risk factors (outcome ~ risk factors) provide predictive power compared to intercept-only null models (Table 9 ). Then, we evaluated blood group's effect on COVID-19 outcomes beyond risk factors using analysis of deviance. Specifically, we compared models including both risk factors and blood group (outcome ~ blood group + risk factors) to those including only risk factors (outcome ~ risk factors), and we found that only the COVID-19 test result outcome (COV+ vs COV-) is significantly better explained by including blood group in addition to risk factors (p<0.02 for both ABO and ABO+Rh, Table 9 ). This result is consistent with our univariate analysis (Table 6 ) , where only COV+ vs COV-cohorts showed significant differences in blood group distribution.
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