The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against COVID-19

Bishajit Sarkar; Md. Asad Ullah; Fatema Tuz Johora; Masuma Afrin Taniya; Yusha Araf

Reverse vaccinology refers to the process of developing vaccines where the novel antigens of a virus or microorganism or organism are detected by analyzing the genomic and genetic information of that particular virus or organism. In reverse vaccinology, the tools of bioinformatics are used for identifying and analyzing these novel antigens. These tools are used to dissect the genome and genetic makeup of a pathogen for developing a potential vaccine. Reverse vaccinology approach of vaccine development also allows the scientists to easily understand the antigenic segments of a virus or pathogen that should be given more emphasis during the vaccine development. This method is a quick, cheap, efficient, easy and cost-effective way to design vaccine. Reverse vaccinology has successfully been used for developing vaccines to fight against many viruses i.e., the Zika virus, Chikungunya virus etc. [