Author: Bishajit Sarkar; Md. Asad Ullah; Fatema Tuz Johora; Masuma Afrin Taniya; Yusha Araf
Title: The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against COVID-19 Document date: 2020_2_11
ID: 7vrm081c_84
Snippet: The current study was designed to construct possible vaccines against the Wuhan Novel Coronavirus 2019 (SARS-CoV-2), which is the cause of the recent outbreak of the deadly viral disease, COVID-19 in China. The pneumonia has already caused the death of several thousands of people worldwide. For this reason, possible vaccines were predicted in this study to fight against this lethal virus. To carry out the vaccine construction, four candidate prot.....
Document: The current study was designed to construct possible vaccines against the Wuhan Novel Coronavirus 2019 (SARS-CoV-2), which is the cause of the recent outbreak of the deadly viral disease, COVID-19 in China. The pneumonia has already caused the death of several thousands of people worldwide. For this reason, possible vaccines were predicted in this study to fight against this lethal virus. To carry out the vaccine construction, four candidate proteins of the virus were identified and selected from the NCBI database. Only highly antigenic sequences were selected for further analysis since the highly antigenic proteins can induce better immunogenic response [185, 201] . Because the nucleocapsid phosphoprotein and surface glycoprotein were found to be antigenic, they were taken into consideration for vaccine construction.
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