Selected article for: "acute heart failure and retrospective study"

Author: Sheshah, Eman; Sabico, Shaun; Albakr, Rashed M.; Sultan, Anmar A.; Alghamdi, Khalaf S.; Al Madani, Khaled; Alotair, Hadil A.; Al-Daghri, Nasser M.
Title: Prevalence of Diabetes, Management and Outcomes among Covid-19 Adult Patients Admitted in a Specialized Tertiary Hospital in Riyadh, Saudi Arabia
  • Cord-id: 34tqy9tb
  • Document date: 2020_11_13
  • ID: 34tqy9tb
    Snippet: This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as per the Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed SARS-CoV2 infection and admitted in King Salman Hospital (KSH) from May 1 to July 31 2020 were included. Medical history, management and outcomes were noted. Males significantly outnumber females (25
    Document: This retrospective study aimed to characterize comorbidities and associated with mortality among hospitalized adults with Covid-19 managed as per the Saudi Ministry of Health protocol in a specialized tertiary hospital in Riyadh, Saudi Arabia. Medical records of 300 adult patients with PCR-confirmed SARS-CoV2 infection and admitted in King Salman Hospital (KSH) from May 1 to July 31 2020 were included. Medical history, management and outcomes were noted. Males significantly outnumber females (259 versus 41). South Asians comprise 41% of all admitted patients. Mortality rate was 10% and highest among Saudi males (28.9%). Type 2 diabetes mellitus (T2DM) was the most common comorbidity (45.7%). Almost all patients (99%) had pneumonia. Patients >50 years were three times more likely to die (confidence interval, CI 1.3-6.9; p=0.01) from Covid-19. Congestive heart failure (odds ratio OR 19.4, CI-1.5-260.0; p=0.02) and acute kidney injury (OR 11.7, CI-4.7-28.6; p<0.001) were significantly associated with higher mortality. Dexamethasone use significantly improved the final outcome based on net reclassification improvement (NRI) and integrated discrimination improvement (IDI) (p<0.05). In this single-center study, T2DM was very common among hospitalized Covid-19 patients. Patients >50 years, those with congestive heart failure and acute kidney injury are at higher risk for worse Covid-19 outcome.

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